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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
6-Thio-2 -deoxyguanosine (6-Thio-dG CAS 789-61-7) is a nucleoside analogue that functions as a telomerase-mediated telomere targeting agent In telomerase-positive cancer cells 6-Thio-dG is incorporated into telomeric DNA inducing rapid telomere dysfunction independent of direct telomerase inhibition which leads to growth arrest and cell death In vitro cancer cell lines exhibit IC50 values ranging from 0 7 to 2 9 M indicating high sensitivity to the compound Normal cells with telomerase-silent status show minimal morphological effects upon 6-Thio-dG exposure In vivo 6-Thio-dG administration inhibits tumor growth and reduces proliferation markers in xenograft models The compound is valuable for investigating telomere biology and as a tool to evaluate telomerase-dependent therapeutic strategies in cancer research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Dasatinib monohydrate is a potent, ATP-competitive dual Src and Bcr-Abl tyrosine kinase inhibitor supplied for in vitro oncology research. Available in solution and solid forms, it is intended for biochemical and cell-based assay applications where a well-characterized kinase inhibitor is required.
High purity suitable for research applications (manufacturer lists ~99.6% purity).
Provided as a 10 mM solution in DMSO for ready-to-use dosing.
Also available as solid material for custom formulation or storage.
Potent Src and Bcr-Abl inhibition supports signaling and mechanistic studies.
Compatible with biochemical and cell-based assay formats.
Documented analytical characterization for reproducible results.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More